Further Reading




Chandrasegaran S. (2017) Recent advances in the use of ZFN-mediated gene editing for human gene therapy. Cell Gene Ther Insights 3: 33-41. 


Chandrasegaran S, Bullen CK and Carroll D. (2017) Genome editing of human embryos: to edit or not to edit, that is the question. J Clin Invest. 127: 3588-3590.


Morange M. (2017) What history tells us XLIV: The construction of the zinc finger nucleases. J Biosci 42: 527-530.


Watanabe K, Kobayashi A, Endo M, Sage-Ono K, Toki S and Ono M. (2017) CRISPR/Cas9-mediated mutagenesis of the dihydroflavanol-4-reductase-B (DFR-B) locus in Japanese morning glory Ipomoea (Pharbitis) nil. Scientific Reports 7: Article number: 10028


Chandrasegaran S and Carroll D. (2016) Origins of programmable nucleases for genome engineering. J Mol Biol 428: 963-989.


Carlson DF, Lancto CA, Zang B, Kim E-S, Walton M, Oldeschulte D, Seabury C, Sonstegard TS and Fahrenkrug SC. (2016) Production of hornless dairy cattle from genome-edited cell lines. Nature Biotechnology 34: 479-481.


Doudna JA and Charpentier E. (2014) The new frontier of genome engineering with CRISPR-Cas9. Science 346: 1077


Ramalingam S, Annaluru N, Kandavelou K and Chandrasegaran S. (2014) TALEN-mediated generation and genetic correction of disease-specific human induced pluripotent stem cells.Current Gene Therapy 14: 461-472. PMID: 25245091

Ramalingam S, London V, Kandavelou K, Cebotaru L, Guggino W, Civin CI and Chandrasegaran S. (2013). Generation and genetic engineering of human induced pluripotent stem cells using designed zinc finger nucleases.StemCells and Development 22: 595-610. PMID: 22931452

Bibikova M, Carroll D, Segal DJ, Trautman JK, Smith J, Kim YG and Chandrasegaran S. (2001). Stimulation of homologous recombination through targeted cleavage by chimeric nucleases.Mol Cell Biol. 21: 289-297. PMID: 11113203

Kim Y-G, Cha J and Chandrasegaran S
. (1996). Hybrid restriction enzymes: Zinc finger fusions to FokI cleavage domain.Proc. Natl. Acad. Sci. USA 93:1156-1160.PMID: 8577732

Li L, Wu LP and Chandrasegaran S. (1992). Functional domains in Fok I restriction endonuclease.Proc. Natl. Acad. Sci. USA 89:4275-4279. PMID: 1584761







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